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Pure Appl. Chem., Vol. 70, No. 11,
pp. 2131, 1998
Production of bioactive alkaloids from Turkish
geophytes*
B. Sener, M. Koyuncu,
F. Bingöl, and F. Muhtar
Gazi University, Faculty of Pharmacy, Department of Pharmacognosy,
P.O.Box 143 06572, Maltepe-Ankara, TURKEY
E-mail: [email protected]
Abstract: The variation in climate in different
regions of Turkey has resulted in a very rich flora and a long history
of many beautiful bulbous plants. Some of them have been cultivated
in European and American gardens as ornamental plants for centuries.
A number of them have also some importance for biological activities.
The bulbs of Galanthus, Narcissus and Leucojum
have an interest because of their content of galanthamine in order
to be used in the treatment of poliomyelitis. For the past thirty
years, 25 % of prescriptions dispensed from the community pharmacies
in Turkey contained active principles that are still extracted from
higher plants. Therefore, medicinal plants have a great potential
for producing new drugs of great benefit to human. Phytochemical
and pharmacological studies have led to the development of several
important compounds as medicinal agents. Turkey exports geophytes
for horticultural purposes mainly collected from the wild. The amount
of material exported from Turkey has increased each year.
The loss of biological diversity due to human activities
has become one of the major problems. It was also directed at the
potential permanent loss of unique chemicals which may have enormous
importance to people. The sustainable utilization of medicinal plant
diversity forms a complex. Saving, studying and using are the three
basic elements of the conservation of bioresources. The major task
of the parties concerned is to cultivate the awareness among the
general public of the importance of conserving the biological diversity
and develop it sustainably. For this purpose, the bulbs of exported
geophytes have been examined for their bioactive compounds. In this
study, the characterization of these compounds along with some regulations
to conserve the native flora will be reviewed.
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* Invited lecture presented at the International
Conference on Bioversity and Bioresources: Conservation and
Utilization, 23-37 November 1997, Phuket, Thailand.
Page last modified 14 April 1999.
Copyright ©1997, 98, 99 International Union of Pure and Applied
Chemistry.
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