Plenary lectures presented at the 5th Florida Heterocyclic Conference,
Gainesville, Florida, USA, 7-10 March 2004
link to conference calendar
The 5th Florida Heterocyclic Conference was held at the University of
Florida in Gainesville, Florida, USA from 7-10 March 2004. About 180
out-of-town participants were treated to 11 excellent plenary lectures
presented by researchers from academia and industry. Three contributions
were presented by industrial chemists J. Macor (Bristol-Myers Squibb,
Wallingford, CT) on dual action receptor antagonists to treat hypertension;
P. Ornstein (Eli Lilly, Indianapolis, IN) on adventures in drug discovery;
and J.D. Armstrong III (Merck &Co., Inc, Rahway, NJ), who reported
on the synthesis and process development of human neurokinin receptor
(hNK-1) antagonists with potential applications for treatment of asthma,
pain, and depression.
Other plenary lecturers included J. Saunders (Cambridge University,
UK) on dynamic combinatorial chemistry: new opportunities for molecular
recognition and catalysis; Guy Queguiner (University of Rouen, France)
on the synthesis and reactions of organometallics of pyridines, quinolines,
and diazines; A. Padwa (Emory University, Atlanta, GA) on cascade processes
for alkaloid synthesis; L. Tietze (University of Göttingen, Germany)
on domino reactions in the synthesis of heterocyclic natural products
and their analogues; C.W. Rees (Imperial College, London, UK) on multiheteroatom
heterocyclic chemistry; T. Tidwell (University of Toronto, Canada) on
the new reactivity of pyridines and piperidines; A. Czarnik (University
of Nevada-Reno, NV) on the applications of reversible hetero-cycle formation
as a signaling sensor in glucose chemosensors; and J.A. Ellman (University
of California, Berkeley, CA) on the new methodology for carbon-carbon
bond formation in the synthesis of nitrogen heterocycles.
The conference also included a full-day short course on the fundamentals
of heterocyclic chemistry, a poster session with 30 contributions, and
a number of short presentations by the participants.
The Florida Heterocyclic Conference supports Arkivoc (Archive for Organic
Chemistry), a free online refereed journal covering all aspects of organic
chemistry, which is available at
The 6th Florida Heterocyclic Conference will be held in Gainesville,
Florida from 27 February to 2 March 2005.
A. Paul Krapcho
International Advisory Committee:
A. Katritzky (USA), C.A. Ramsden (UK), C. Rees (UK), E. Scriven (USA).