New schemes for the synthesis of glycolipid oligosaccharide chains
N. E. Nifantiev, A. A. Sherman, O. N. Yudina, P. E. Cheshev, Y. E. Tsvetkov, E. A. Khatuntseva, A. V. Kornilov, and A. S. Shashkov
N.D. Zelinsky Institute of Organic Chemistry, Russian
Academy of Sciences, Leninsky Prospect 47, B-334 Moscow 119991, Russia
Abstract: The driving force for the constant improvement and
development of synthetic methodologies in carbohydrate chemistry is
the importance of natural oligosaccharide chains in numerous biological
phenomena such as cell growth, differentiation, adhesion, etc. Here,
we report our syntheses of the spacer-armed oligosaccharides of sialylated
lacto- and neo- lacto-, globo-, ganglio-,
and sulfoglucuronylparagloboside-series, which include new rationally
designed synthetic blocks, efficient solutions for the stereoselective
construction of glycosidic bonds, and novel protection group strategies.
*Plenary lecture presented at the XVII Mendeleev Congress on General and Applied Chemistry, Kazan, Tatarstan, Russia, 21 -26 September 2003. Other presentations are published in this issue, pp. 1605-1798.
Page last modified 23 September 2004.
Copyright © 2004 International Union of Pure and Applied Chemistry.
Questions or comments about IUPAC, please contact, the Secretariat.
Questions regarding the website, please contact web
manager.
