I  U  P  A  C

 

 

 

News & Notices

Organizations & People

Standing Committees

Divisions

Projects

Reports

Publications
. . CI
. . PAC
. . Macro. Symp.

. . Books
. . Solubility Data

Symposia

AMP

Links of Interest

Search the Site

Home Page

 

Pure Appl. Chem. Vol. 74, No. 5, pp. 835-855 (2002)

Pure and Applied Chemistry

Vol. 74, Issue 5

ANALYTICAL CHEMISTRY DIVISION
INTERDIVISIONAL WORKING PARTY ON HARMONIZATION OF QUALITY ASSURANCE

Harmonized guidelines for single-laboratory validation of methods of analysis (IUPAC Technical Report)

Michael Thompson1, Stephen L. R. Ellison2, and Roger Wood3,**

1Department of Chemistry, Birkbeck College (University of London), London WC1H 0PP, UK; 2Laboratory of the Government Chemist, Queens Road, Teddington, Middlesex TW11 0LY, UK; 3Food Standards Agency, c/o Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK

Abstract: Method validation is one of the measures universally recognized as a necessary part of a comprehensive system of quality assurance in analytical chemistry. In the past, ISO, IUPAC, and AOAC International have cooperated to produce agreed protocols or guidelines on the "Design, conduct and interpretation of method performance studies" [1], on the "Proficiency testing of (chemical) analytical laboratories" [2], on "Internal quality control in analytical chemistry laboratories" [3], and on "The use of recovery information in analytical measurement" [4]. The Working Group that produced these protocols/guidelines has now been mandated by IUPAC to prepare guidelines on the single-laboratory validation of methods of analysis. These guidelines provide minimum recommendations on procedures that should be employed to ensure adequate validation of analytical methods.

A draft of the guidelines has been discussed at an International Symposium on the Harmonization of Quality Assurance Systems in Chemical Laboratory, the proceedings from which have been published by the UK Royal Society of Chemistry.

** Corresponding author.

> Download full text of the report [pdf file - 226K]

> View corresponding project

[Back to Contents]


 

Page last modified 27 June 2002.
Copyright © 2002 International Union of Pure and Applied Chemistry.
Questions or comments about IUPAC, please contact, the Secretariat.
Questions regarding the website, please contact web manager.