Title: Metabolism terms
Chairman: Paul W.
Bachmann, Don Birkett,
Mike Boberg, Nick
Bodor, Gordon Gibson
(Editor Xenobiotica), Dave
Hawkins (Editor Biotransformations), Gabrielle
Hawksworth (Chairperson Drug Metab. Sect. IUPHAR), Jack Hinson
(Editor Drug Metabolism Reviews), Hiroshi
Masumoto, Ray Novak
(Editor Drug Metabolism & Disposition), Phillip
Portoghese (Editor J. Medicinal Chemistry), Teresa
Serafini, and Nicolas
To compile a list of terms with their definitions in the area
of drug metabolism and to disseminate the list to the scientific community.
About 150 terms directly related to the field of drug metabolism
will be compiled and defined by this expert group for dissemination
to the scientific community. This will help achieve a common definition
base across the various publications in this field. In addition, a
more uniform use of these terms should assist in the future construction
of databases pertaining to this field's information.
The working party has pared-down its initial, all-inclusive list
of over 600 terms related to drug metabolism, to a focused list of
about 170 terms. The latter better represents just those terms that
are the most relevant for medicinal chemistry. To generate definitions,
the shortened list has been divided evenly among the 15 experts who
are participating on this task group (ca. 11 terms each). About one-third
of the terms now have draft definitions. When the latter are complete,
they will be reviewed by the entire working party for finalization.
It is anticipated that this project will be completed before the end
of 2002. Several of the task group's experts hold editorial positions
on major journals associated with medicinal chemistry and drug metabolism,
and they would also like to publish the terms (after the terms' appearance
(May 2007) All terms have been defined and while most are
also finalized among the Working Party, several are undergoing minor
revision. At the same time, the overall formatting is being adjusted
to the latest ICTNS requirements. It is now anticipated that these
terms will be ready for publication by 2008.
Last Update: 8 May 2007
<project announcement published