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43rd IUPAC Council Meeting

Nominee for Vice President

Nicole J. Moreau (France)

Nicole J. Moreau

After 10 years of research in organic synthesis, terpenes, steroids, and sugars, Professor Nicole J. Moreau successfully designed the first purification, using affinity chromatography, of enzymes that inactivate aminoglycoside antibiotics. Her research is at the interface of chemistry and life sciences, and she continues to study the mode of action of antibiotics and the ways bacteria can resist them. She developed a mean throughput screening system in order to find molecules able to be active against resistant bacteria, for instance inhibitors of efflux pumps or of inactivating enzymes. She has also researched molecular pharmacology, structure-activity relationships and synthesis of analogues of active compounds together with molecular modeling and docking calculations. In 2005, she launched, together with CNRS and Rhodia, a new program on fine chemistry using bioconversions.

Education and Career
Moreau received an M.S. in physical chemistry from the University of Paris (Sorbonne). She obtained a doctorate in physical sciences (chemistry distinction) in 1967 from Orsay University.

Since 1999, Moreau has been a professor at Ecole Nationale Supérieure de Chimie de Paris (ENSCP), where she is the leader of the Laboratory of Biochemistry. From 1994–1999 she was a professor in the Laboratory of Molecular Research on Antibiotics at the Paris 6 University (Pierre and Marie Curie). In 1973, she was a postdoctoral fellow in the laboratory of Dr. J. S. Pitton at the Medical Microbiology Institute in Geneva, Switzerland. Moreau began service with the Centre National de la Recherche Scientifique (CNRS) in 1962, where she was “directeur de recherche” from 1979 to 1992. In 1972, Moreau joined the chemistry laboratory of Prof. Le Goffic at Ecole Normale Supérieure in Paris, where she worked until 1993.

Moreau has authored more than 80 publications, given more than 90 conferences or oral presentations, and supervised 25 Ph.D and 22 M.S. students and 10 post-doctoral fellows. She is responsible for teaching at the interface of chemistry and life sciences at the Ecole Nationale Supérieure de Chimie de Paris and is a member of the Administration Committee of the French Society of Biochemistry and Molecular Biology.

IUPAC Activities
Since 2000, Moreau has been an elected member of the Bureau and also a member of the Project Committee. She has served as vice president and currently is general secretary of the French National Committee for Chemistry. She has been a member of the French Delegation since 1995.

Related Professional Activities
Moreau has held a number of leadership positions with leading chemistry institutions. She has served as chargé de mission, State Department of Research (Ministère de la Recherche), deputy director of the Drugs department (1984–1989) and has been chargé de mission (1993–1997), then deputy director (1998–2003), at CNRS, Department of Chemical Sciences. Since 2003, she remained chargé de mission for natural substances for the CNRS Chemistry Department and International Relationships Direction.

She was secretary (1989–1997), then president (1997-1999) of EUCHEM, European Chemistry; president of GESA; Study Group of Structure-Activity Relationships (1990); vice-president of the French National Committee for Chemistry, CNC, IUPAC NAO (1994–2002). In addition, she is a long-time member of the French Chemical Society, French Microbiology Society, and the French Biochemistry and Molecular Biology Society.

Moreau was awarded the Prix de l’Académie de Pharmacie, Paris, in 1974, and the Chevalier de l’Ordre National du Mérite, awarded by the State Department of Research, in 2002. In 2004 she received the Silver Medal of the International Foundation of la Maison de la Chimie.


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at 43rd IUPAC Council Meeting

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