Solubility and crystallization in biological fluids and the problems
of life and health
I. Gutzow1, S. Atanassova2, and K. Neykov2
1 Institute of Physical Chemistry, Bulgarian Academy
of Sciences, Sofia 1113, Bulgaria; 2 Chair of Urology, The Medical University,
Sofia 1431, Bulgaria
Abstract: An analysis is given of several biologically important
processes, connected with the crystallization and kinetics of liophilization
in aqueous physiological solutions. These are glass formation and vitrification
of life, precipitation of slightly soluble salts and kinetics of crystallization
in human urine, and the solution of CaOX concretions under the influence
of biocompatible solubilizators, which are normal constituents of human
urine. The problems investigated experimentally are treated in the framework
of the capillary theory of nucleation and the Debye–Hückel model of
ionic solutions.
* Lectures presented at the 10th International Symposium
on Solubility Phenomena, Varna, Bulgaria, 22 -26 July 2002. Other
lectures are published in this issue, pp. 1785-1920.
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