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Pure Appl. Chem. Vol.
74, No. 4, pp. 511-517 (2002)
Pure and Applied Chemistry
Vol. 74, Issue 4
Biodiversity: A wonderful source of exciting new pharmacophores.
Further to a new theory of memory*
Atta-ur-Rahman and M. Iqbal Choudhary
H. E. J. Research Institute of Chemistry, International
Center for Chemical Sciences, University of Karachi, Karachi-75270,
Abstract: The diverse biological resources in nature are vast
factories of chemical diversity. With the recent advances in the biological
and chemical sciences it is now easier than ever to explore the potential
uses of immense biological resources in a sustainable manner. Our investigations
focused on the bioprospecting of both terrestrial and marine organisms
have led to the discovery of a number of interesting chemical compounds.
The discovery of a new class of cholinesterase, a-glucosidase
and phosphodiesterase I inhibitors, several new antioxidants, and other
classes of bioactive natural products is presented. The theory of the
chemical basis of memory through hydrogen bonding in the brain is further
* Lecture presented at the 3rd IUPAC International
Conference on Biodiversity (ICOB-3), Antalya, Turkey, 3-8 November 2001.
Other presentations are presented in this issue, pp. 511584.
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