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Pure Appl. Chem. Vol.
73, No. 7, pp. 10331039 (2001)
Pure and Applied
Vol. 73, Issue
Integrating natural product synthesis and combinatorial
Department of Chemistry, University
of Southampton, Southampton SO17 1BJ, United Kingdom
Abstract: The fields of natural product total
synthesis and combinatorial chemistry have major differences as well
as much in common. Unique to combinatorial chemistry is the need to
devise rapid and efficient methods for parallel synthesis and purification,
while an area of overlap is the targeting of natural product scaffolds
for combinatorial libraries. Both these aspects are illustrated with
examples from our research.
*Lecture presented at the 38th IUPAC
Congress/World Chemistry Congress 2001, Brisbane, Australia, 1-6 July
2001. Other presentations are published in
this issue, pp.1033-1145.
Dedicated to the memory of my father, S. T .Arasu (1928-2001).
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