32 No. 4
|Making an imPACt
||Recent IUPAC technical reports and recommendations that affect the many fields of pure and applied chemistry.
See also www.iupac.org/publications/pac
Electrochemical Nucleic Acid–Based Biosensors: Concepts, Terms, and Methodology (IUPAC Technical Report)
Jan Labuda, Ana Maria Oliveira Brett, Gennady Evtugyn, Miroslav Fojta, Marco Mascini, Mehmet Ozsoz, Ilaria Palchetti, Emil Paleček, and Joseph Wang
Pure and Applied Chemistry, 2010
Vol. 82, No. 5, pp. 1161–1187
An electrochemical nucleic acid–based biosensor is a biosensor that integrates a nucleic acid as the biological recognition element and an electrode as the electrochemical signal transducer. This report provides concepts, terms, and methodology related to biorecognition elements, detection principles, type of interactions to be addressed, and construction and performance of electrochemical nucleic acid–based biosensors, including their critical evaluation, which should be valuable for a wide audience, including academic, biomedical, environmental, food-testing, and drug-developing laboratories and sensor producers.
last modified 1 July 2010.
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